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KMID : 1039420150490040331
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Journal of Pathology and Translational Medicine
2015 Volume.49 No. 4 p.331 ~ p.334
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A Rare Case of Primary Tubular Adenocarcinoma of the Thymus, Enteric Immunophenotype: A Case Study and Review of the Literature
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Jung Hae-Yoen
Cho Hyun-Deuk
Chung Jin-Haeng
Bae Sang-Byoung
Lee Ji-Hye
Lee Hyun-Ju
Jang Si-Hyong
Oh Mee-Hye
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Abstract
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Thymic carcinomas are uncommon malignant tumors, and thymic adenocarcinomas are extremely rare. Here, we describe a case of primary thymic adenocarcinoma in a 59-year-old woman. Histological examination of the tumor revealed tubular morphology with expression of cytokeratin 20 and caudal-type homeobox 2 according to immunohistochemistry, suggesting enteric features. Extensive clinical and radiological studies excluded the possibility of an extrathymic primary tumor. A review of the literature revealed only two global cases of primary tubular adenocarcinomas of the thymus with enteric immunophenotype.
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KEYWORD
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Thymus gland, Adenocarcinoma, Keratin-20, Caudal type homeobox 2
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